coagulation factor ix การใช้

The conserved domain NIDO, was > 99 % similar to coagulation factor IX, also known as Factor IX ( F9 ).
:Specifically activates several components of the blood clotting system, including coagulation factor X, coagulation factor IX and protein C by cleavage of-Arg-bonds.
Defective calcium binding to coagulation factor IX contributes to the development of hemophilia B . Individuals afflicted with this hereditary disease tend to develop hemorrhages, potentially leading to life-threatening conditions.
The product, known as Coagulation Factor IX, offers a virus-free alternative to current human plasma-derived blood factors for hemophiliacs because it is a genetically engineered, or recombinant, form, the FDA said.
The cause of hemophilia B is decreased activity or deficiency of blood coagulation factor IX . Point mutations resulting in decreased affinity of factor IX to calcium are thought to be implicated in this bleeding disorder.